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Application of nitrogen generator in pharmaceutical industry

2020-09-22 H:30:22
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Nitrogen generator for pharmaceutical industry is mainly used in pharmaceutical production, storage, packaging, packaging and other fields.

In general, water for injection (penicillin, etc.) and large infusion (such as amino acid) that are easy to oxidize need to be protected with flushing nitrogen, otherwise the liquid medicine is easy to oxidize during storage, that is, deterioration. Generally, nitrogen injection before and after nitrogen injection (or single injection of nitrogen) is used before packaging to reduce the oxygen concentration in ampoules or infusion bottles to less than 0.5%, which can ensure the quality of drugs for a long time. At present, the equipment purchased by general air separation plant manufacturers is about 5-20m3 / h, and the purity is 99.99%. The difference between medical nitrogen generator and other nitrogen generating equipment is that the parts in contact with drugs or liquid drugs are made of stainless steel, and the sterilization requirements meet GMP standards of pharmaceutical industry. The material of the equipment is stainless steel, and the sterilization and filtering device is installed at the nitrogen outlet of the equipment. In addition, due to the high overall requirements of pharmaceutical plants for equipment, they usually have high-end configuration.

There are also API manufacturers that need nitrogen protection. The process of using nitrogen is more like a fine chemical plant. The purity is usually 99-99.9%, but the dosage varies with the scale of the plant, but it is much larger than that of the pharmaceutical nitrogen generator.


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